Chorioretinal Vascular Oxygen Tension Changes in Response to Light Flicker
نویسندگان
چکیده
منابع مشابه
Chorioretinal vascular oxygen tension in spontaneously breathing anesthetized rats.
PURPOSE To establish baseline and variability of oxygen tension (PO(2)) measurements in the choroid, retinal arteries, capillaries, and veins of spontaneously breathing anesthetized rats and determine the effect of a moderate surgical procedure on the chorioretinal PO(2). METHODS Our previously established optical section phosphorescence imaging technique was utilized to measure PO(2) in the ...
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Vascular response to changes in blood oxygen tension under various blood Jlow rates. Am. peripheral vascular response to Pa0, ranging from 25 to 2,500 mm Hg was systematically studied in the hindlimbs of dogs under constant-flow perfu-sion. With cross-circulation experiments using two dogs, a distinction between reflex-mediated response and local effects was possible. While reflex and local mec...
متن کاملThree-dimensional mapping of chorioretinal vascular oxygen tension in the rat.
PURPOSE An optical section phosphorescence lifetime imaging system was developed for three-dimensional mapping of oxygen tension (P(O2)) in chorioretinal vasculatures. METHODS A laser line was projected at an oblique angle and scanned on the retina after intravenous injection of an oxygen-sensitive molecular probe to generate phosphorescence optical section images. An automated software algor...
متن کاملRetinal Vascular and Oxygen Temporal Dynamic Responses to Light Flicker in Humans
Purpose To mathematically model the temporal dynamic responses of retinal vessel diameter (D), oxygen saturation (SO2), and inner retinal oxygen extraction fraction (OEF) to light flicker and to describe their responses to its cessation in humans. Methods In 16 healthy subjects (age: 60 ± 12 years), retinal oximetry was performed before, during, and after light flicker stimulation. At each ti...
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PURPOSE Light flicker has been shown to stimulate retinal neural activity, increase blood flow, and alter inner retinal oxygen metabolism (MO2) and delivery (DO2). The purpose of the study was to determine the change in MO2 relative to DO2 due to light flicker stimulation in humans, as assessed by the inner retinal oxygen extraction fraction (OEF). METHODS An optical imaging system, based on ...
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ژورنال
عنوان ژورنال: Investigative Opthalmology & Visual Science
سال: 2006
ISSN: 1552-5783
DOI: 10.1167/iovs.06-0291